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Proteomic Signature and mRNA Expression in Hippocampus of SAMP8 and SAMR1 Mice during Aging

1 Dec 2022

Abstract excerpt

Aging is a complex process often accompanied by cognitive decline that represents a risk factor for many neurodegenerative disorders including Alzheimer's and Parkinson's disease. The molecular mechanisms involved in age-related cognitive decline are not yet fully understood, although increased neuroinflammation is considered to play a significant role. In this study, we characterized a proteomic view of the...

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PMID: 36499421
DOI: 10.3390/ijms232315097

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