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Article

Immunodominance in allergic T-cell reactivity to Japanese cedar in different geographic cohorts.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Dec 2016

Oseroff Carla, Pham John, Frazier April, Hinz Denise, Sidney John, Paul Sinu, Greenbaum Jason A, Vita Randi, Peters Bjoern, Schulten Véronique, Sette Alessandro

Abstract excerpt

BACKGROUND: Japanese cedar (JC) pollen is a common trigger for allergic rhinitis in Japan. Pollen proteins targeted by IgE, including Cry j 1 and Cry j 2, and isoflavone reductase (IFR) have been identified. OBJECTIVE: To compare antigen-specific IgE titers and T-cell responses to JC pollen-derived extract and peptides in cohorts with high and low pollen exposure. METHODS: Peripheral blood mononuclear cells from...

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Identifiers

PMID: 27979027
DOI: 10.1016/j.anai.2016.10.014
PMCID: PMC5172395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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