Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A copy number variation genotyping method for aneuploidy detection in spontaneous abortion specimens.

Prenatal diagnosis - 1 Feb 2017

Chen Songchang, Liu Deyuan, Zhang Junyu, Li Shuyuan, Zhang Lanlan, Fan Jianxia, Luo Yuqin, Qian Yeqing, Huang Hefeng, Liu Chao, Zhu Huanhuan, Jiang Zhengwen, Xu Chenming

Abstract excerpt

OBJECTIVE: Chromosomal abnormalities such as aneuploidy have been shown to be responsible for causing spontaneous abortion. Genetic evaluation of abortions is currently underperformed. Screening for aneuploidy in the products of conception can help determine the etiology. We designed a high-throughput ligation-dependent probe amplification (HLPA) assay to examine aneuploidy of 24 chromosomes in miscarriage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Spontaneous
Share to Aneuploidy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Aberrations

Share to Chromosome Disorders

Share to Comparative Genomic Hybridization

Share to DNA Copy Number Variations

Share to Genotyping Techniques

Share to High-Throughput Nucleotide Sequencing

Source

Identifiers

PMID: 27977861
DOI: 10.1002/pd.4986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A copy number variation genotyping method for aneuploidy detection in spontaneous abortion specimens.PMID 27977861Read ↗

A Novel System for the Detection of Spontaneous Abortion-Causing Aneuploidy and Its Erroneous Chromosome Origins through the Combination of Low-Pass Copy Number Variation Sequencing and NGS-Based STR TestsSemantic proximity Read ↗

Clinical Utility of Gene Chip Technology for Genetic Diagnosis in 708 Cases of Spontaneous Abortion TissuesSemantic proximity Read ↗

Comprehensive genetic analysis of pregnancy loss by chromosomal microarrays: outcomes, benefits, and challenges.Semantic proximity Read ↗

Analysis of Chromosomal Copy Number in First-Trimester Pregnancy Loss Using Next-Generation SequencingSemantic proximity Read ↗

Clinical utilization of chromosomal microarray analysis for the genetic analysis in subgroups of pregnancy lossSemantic proximity Read ↗

Improved assay performance of single nucleotide polymorphism array over conventional karyotyping in analyzing products of conception.Semantic proximity Read ↗

Analysis of copy number variations and possible candidate genes in spontaneous abortion by copy number variation sequencingSemantic proximity Read ↗

Aneuploidies detection in miscarriages and fetal deaths using multiplex ligation-dependent probe amplification: an alternative for speeding up results?Semantic proximity Read ↗

Clinical Validation of Novel Chip-Based Digital PCR Platform for Fetal Aneuploidies ScreeningSemantic proximity Read ↗

Chromosomal Aneuploidy Associated With Clinical Characteristics of Pregnancy LossSemantic proximity Read ↗

Prevalence of chromosomal abnormalities identified by copy number variation sequencing in high-risk pregnancies, spontaneous abortions, and suspected genetic disordersSemantic proximity Read ↗

Chromosomal copy number variations in products of conception from spontaneous abortion by next-generation sequencing technologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.