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Article

Comprehensive genetic analysis of pregnancy loss by chromosomal microarrays: outcomes, benefits, and challenges.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2017

Sahoo Trilochan, Dzidic Natasa, Strecker Michelle N, Commander Sara, Travis Mary K, Doherty Charles, Tyson R Weslie, Mendoza Arturo E, Stephenson Mary, Dise Craig A, Benito Carlos W, Ziadie Mandolin S, Hovanes Karine

Abstract excerpt

PURPOSE: Chromosomal microarray analysis (CMA) is currently considered first-tier testing in pediatric care and prenatal diagnosis owing to its high diagnostic sensitivity for chromosomal imbalances. The aim of this study was to determine the efficacy and diagnostic power of CMA in both fresh and formalin-fixed paraffin-embedded (FFPE) samples of products of conception (POCs). METHODS: Over a 44-month period,...

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Abortion, Spontaneous
Aneuploidy
Chromosome Aberrations
Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

In Situ Hybridization, Fluorescence

Paraffin Embedding

Prenatal Diagnosis

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PMID: 27337029
DOI: 10.1038/gim.2016.69

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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