Article
Improved assay performance of single nucleotide polymorphism array over conventional karyotyping in analyzing products of conception.
Journal of the Chinese Medical Association : JCMA - 1 Jul 2015
Lin Shao-Bin, Xie Ying-Jun, Chen Zheng, Zhou Yi, Wu Jian-Zhu, Zhang Zhi-Qiang, Shi Shan-Shan, Chen Bao-Jiang, Fang Qun
Abstract excerpt
BACKGROUND: Conventional karyotyping has been a routine method to identify chromosome abnormalities in products of conception. However, this process is being transformed by single nucleotide polymorphism (SNP) array, which has advantages over karyotyping, including higher resolution and dispensing with cell culture. Therefore, the purpose of this study was to evaluate the advantage of high-resolution SNP array in...
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