Article

Comprehensive bioinformatics analysis reveals CLCA1 and ZG16 as predictive biomarkers of malignant progression in colorectal cancer

2024-09-23

Abstract excerpt

<title>Abstract</title> <p>Background Colorectal cancer (CRC) is one of the most common malignant tumors. CLCA1 and ZG16 are lowly expressed in CRC, and we wanted to investigate whether they could be prognostic biomarkers for the malignant progression of CRC. Methods 12,195 DEGs and 12,071 DEGs were identified through the GSE39582 dataset and TCGA dataset, and then 50 coexisting genes were selected for further...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2b499302-6738-5620-bb41-d751b6d41753
DOI: 10.21203/rs.3.rs-4930170/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comprehensive bioinformatics analysis reveals CLCA1 and ZG16 as predictive biomarkers of malignant progression in colorectal cancerDOI 10.21203/rs.3.rs-4930170/v1Read

Differential Expression Analysis Revealing CLCA1 to Be a Prognostic and Diagnostic Biomarker for Colorectal CancerSemantic proximity Read

Loss of ZG16 is regulated by miR-196a and contributes to stemness and progression of colorectal cancerSemantic proximity Read

Identification of Genes Related to Clinicopathological Characteristics and Prognosis of Patients with Colorectal CancerSemantic proximity Read

Calcium Binding Protein S100A16 Expedites Proliferation, Invasion and EMT Process in Gastric CancerSemantic proximity Read

LncRNA SNHG16 Facilitates Liver Metastases of Colorectal Cancer by Modulating Circulating Tumor Cells (CTCs) Epithelial-Mesenchymal Transition (EMT) via a Positive Feedback Loop with YAP1/TEAD1 ComplexSemantic proximity Read

MiR-17-3p Facilitates Aggressive Cell Phenotypes in Colon Cancer by Targeting PLCD1 Through Affecting KIF14.Semantic proximity Read

Loss of ZG16 is associated with molecular and clinicopathological phenotypes of colorectal cancerSemantic proximity Read

The expression and prognostic significance of CCNB1 in colorectal cancer based on TCGA databaseSemantic proximity Read

CLCA1 Has a Prognostic Indicator for the Colorectal Cancer by Weighted Gene Co-Expression Network AnalysisSemantic proximity Read

Targeting PLA2G16, a lipid metabolism gene, by Ginsenoside Compound K to suppress the malignant progression of colorectal cancerSemantic proximity Read

Multi-omics analysis identifies CLDN1 as a key regulator of gallbladder cancer progression and prognosisSemantic proximity Read

LncRNA SNHG16 facilitates the liver metastasis of colorectal cancer by modulating circulating tumor cell epithelial-mesenchymal transition via a positive feedback loop with the YAP1/TEAD1 complexSemantic proximity Read