Article
Prior knowledge guided eQTL mapping for identifying candidate genes.
BMC bioinformatics - 13 Dec 2016
Wang Yunli, Richard Rene, Pan Youlian
Abstract excerpt
BACKGROUND: Expression quantitative trait loci (eQTL) mapping is often used to identify genetic loci and candidate genes correlated with traits. Although usually a group of genes affect complex traits, genes in most eQTL mapping methods are considered as independent. Recently, some eQTL mapping methods have accounted for correlated genes, used biological prior knowledge and applied these in model species such as...
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