Article
Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster.
Genetics - 1 Aug 2016
Edwards Stefan M, Sørensen Izel F, Sarup Pernille, Mackay Trudy F C, Sørensen Peter
Abstract excerpt
Predicting individual quantitative trait phenotypes from high-resolution genomic polymorphism data is important for personalized medicine in humans, plant and animal breeding, and adaptive evolution. However, this is difficult for populations of unrelated individuals when the number of causal variants is low relative to the total number of polymorphisms and causal variants individually have small effects on the...
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