Article
Explaining the genetic basis of complex quantitative traits through prediction models.
Journal of computational biology : a journal of computational molecular cell biology - 1 Dec 2010
Luaces Oscar, Quevedo José R, Pérez-Enciso Miguel, Díez Jorge, Del Coz Juan José, Bahamonde Antonio
Abstract excerpt
The functional characterization of genes involved in many complex traits (phenotypes) of plants, animals, or humans can be studied from a computational point of view using different tools. We propose prediction--from the machine learning point of view--to search for the genetic basis of these traits. However, trying to predict an exact value of a phenotype can be too difficult to obtain a confident model, but...
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