Article
Dormancy Stems the Tide of Chemotherapy.
Cancer cell - 12 Dec 2016
Pal Deepali, Heidenreich Olaf, Vormoor Josef
Abstract excerpt
In this issue of Cancer Cell, Ebinger et al. describe rare, non-cycling blasts in acute lymphoblastic leukemia that combine the phenotypes of dormancy, stemness, and chemo-resistance. This novel in vivo model for dormant blasts will facilitate the dissection of the niche and the development of therapies targeting the leukemic microenvironment.
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