Article
Receptor-interacting protein 2 (RIP2) gene polymorphisms are associated with increased risk of subclinical atherosclerosis and clinical and metabolic parameters. The Genetics of Atherosclerotic Disease (GEA) Mexican study.
Experimental and molecular pathology - 1 Feb 2017
Posadas-Sánchez Rosalinda, Ángeles-Martínez Javier, Pérez-Hernández Nonanzit, Rodríguez-Pérez José Manuel, López-Bautista Fabiola, Villarreal-Molina Teresa, Fragoso José Manuel, Posadas-Romero Carlos, Vargas-Alarcón Gilberto
Abstract excerpt
The receptor-interacting protein 2 (Rip2) is a serine/threonine kinase involved in multiple nuclear factor-κB (NFκB) activation pathways and is a key regulator of cellular lipid metabolism and cardiovascular disease. The aim of the present study was to evaluate the role of RIP2 gene polymorphisms as susceptibility markers for subclinical atherosclerosis (SA). Using an informatics analysis, four RIP2 gene...
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