Article
Cardiac manifestations of congenital LMNA-related muscular dystrophy in children: three case reports and recommendations for care.
Cardiology in the young - 1 Aug 2017
Heller Felice, Dabaj Ivana, Mah Jean K, Bergounioux Jean, Essid Aben, Bönnemann Carsten G, Rutkowski Anne, Bonne Gisèle, Quijano-Roy Susana, Wahbi Karim
Abstract excerpt
Skeletal and cardiac muscle laminopathies, caused by mutations in the lamin A/C gene, have a clinical spectrum from congenital LMNA-related muscular dystrophy to later-onset Emery-Dreifuss muscular dystrophy, limb girdle muscular dystrophy, and dilated cardiomyopathy. Although cardiac involvement is observed at all ages, it has only been well described in adults. We present the evolution of cardiac disease in...
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