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Article

Thyroid hormone suppresses expression of stathmin and associated tumor growth in hepatocellular carcinoma

9 Dec 2016

Abstract excerpt

Abstract Stathmin (STMN1), a recognized oncoprotein upregulated in various solid tumors, promotes microtubule disassembly and modulates tumor growth and migration activity. However, the mechanisms underlying the genetic regulation of STMN1 have yet to be elucidated. In the current study, we report that thyroid hormone receptor (THR) expression is negatively correlated with STMN1 expression in a subset of clinical...

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PMID: 27934948
DOI: 10.1038/srep38756

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