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Article

Molecular mechanisms of HPV mediated neoplastic progression

25 Nov 2016

Abstract excerpt

Human Papillomavirus is the major etiological agent in the development of cervical cancer but not a sufficient cause. Despite significant research, the underlying mechanisms of progression from a low-grade squamous intraepithelial lesion to high grade squamous intraepithelial lesion are yet to be understood. Deregulation of viral gene expression and host genomic instability play a central role in virus-mediated...

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PMID: 27933097
DOI: 10.1186/s13027-016-0107-4

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