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Carcinogenesis Associated with Human Papillomavirus Infection. Mechanisms and Potential for Immunotherapy

1 Jul 2019

Abstract excerpt

Human papillomavirus (HPV) infection is responsible for approximately 5% of all cancers and is associated with 30% of all pathogen-related cancers. Cervical cancer is the third most common cancer in women worldwide; about 70% of cervical cancer cases are caused by the high-risk HPVs (HR HPVs) of genotypes 16 and 18. HPV infection occurs mainly through sexual contact; however, viral transmission via horizontal and...

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PMID: 31509729
DOI: 10.1134/s0006297919070095

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