Article
Anatomical location differences between mutated and wild-type isocitrate dehydrogenase 1 in low-grade gliomas.
The International journal of neuroscience - 1 Oct 2017
Yu Jinhua, Shi Zhifeng, Ji Chunhong, Lian Yuxi, Wang Yuanyuan, Chen Liang, Mao Ying
Abstract excerpt
Anatomical location of gliomas has been considered as a factor implicating the contributions of a specific precursor cells during the tumor growth. Isocitrate dehydrogenase 1 (IDH1) is a pathognomonic biomarker with a significant impact on the development of gliomas and remarkable prognostic effect. The correlation between anatomical location of tumor and IDH1 states for low-grade gliomas was analyzed...
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