Article
Retinoid derivative Tp80 exhibits anti-hepatitis C virus activity through restoration of GI-GPx expression.
Journal of medical virology - 1 Jul 2017
Nguyen Bao Ngoc, Okuno Yukiko, Ajiro Masahiko, Iida Kei, Denawa Masatsugu, Yamamoto Makoto, Sakamoto Naoya, Kagechika Hiroyuki, Hagiwara Masatoshi
Abstract excerpt
Hepatitis C virus (HCV) is a positive-sense single-stranded RNA virus with an estimated infection in ∼180 million people worldwide, and its chronic infection leads to development of cirrhosis and hepatocellular carcinoma. Although recent development of direct acting antiviral (DAA) compounds improved anti-HCV regimens, alternative therapeutic compounds are still demanded due to an expected emergence of escape...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
