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Article

The Type III Secretion System Effector SptP of Salmonella enterica Serovar Typhi.

Journal of bacteriology - 15 Feb 2017

Johnson Rebecca, Byrne Alexander, Berger Cedric N, Klemm Elizabeth, Crepin Valerie F, Dougan Gordon, Frankel Gad

Abstract excerpt

Strains of the various Salmonella enterica serovars cause gastroenteritis or typhoid fever in humans, with virulence depending on the action of two type III secretion systems (Salmonella pathogenicity island 1 [SPI-1] and SPI-2). SptP is a Salmonella SPI-1 effector, involved in mediating recovery of the host cytoskeleton postinfection. SptP requires a chaperone, SicP, for stability and secretion. SptP has 94%...

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Identifiers

PMID: 27920299
DOI: 10.1128/JB.00647-16
PMCID: PMC5287405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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