Article
The 'normal' range of FMR1 triple CGG repeats may be associated with primary ovarian insufficiency in China.
Reproductive biomedicine online - 1 Feb 2017
Lu Cui-Ling, Li Rong, Chen Xin-Na, Xu Yang-Ying, Yan Li-Ying, Yan Jie, Zhang Yao-Yao, Jin Hong-Yan, Zhang Wen-Xin, Qiao Jie, Zhen Xiu-Mei
Abstract excerpt
The aim of this study was to investigate the relationship between normal Fragile X mental retardation gene 1 (FMR1) CGG repeat numbers and primary ovarian insufficiency (POI) occurrence or subsequent resumption of ovarian function. A total of 122 women with POI and 105 controls were followed up and analysed in our centre. The prevalence of premutation and intermediate range of FMR1 CGG repeats in Han Chinese...
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