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Article

Sickle cell disease: an inherited thrombophilia

2 Dec 2016

Abstract excerpt

Activation of the hemostatic system occurs in patients with sickle cell disease. The extent to which this activation contributes to sickle cell pathophysiology is uncertain. Clinical trials of anticoagulants or platelet inhibitors have demonstrated the ability to decrease biomarkers of hemostatic activation, but this has generally not resulted in improvement in clinically relevant outcomes. Venous thromboembolism...

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Share to Hemoglobinopathies and Related Disorders
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Identifiers

PMID: 27913540
DOI: 10.1182/asheducation-2016.1.640

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