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Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation

28 Nov 2016

Abstract excerpt

Blastocyst implantation is a complex process requiring coordination of a dynamic sequence of embryo-uterine interactions. Blood vessels enter the uterus from the mesometrium, demarcating the uterus into mesometrial (M) and antimesometrial (AM) domains. Implantation occurs along the uterine longitudinal axis within specialized implantation chambers (crypts) that originate within the evaginations directed from the...

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PMID: 27911818
DOI: 10.1073/pnas.1614946113

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