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Identification of Marek’s disease virus genes associated with virulence of US strains

11 Jun 2019

Abstract excerpt

Marek's disease virus (MDV) is the most well-cited example of vaccine-driven virulence evolution. MDV induces a lymphoproliferative disease in chickens, which is currently controlled by widespread vaccination of flocks. Unfortunately, Marek's disease (MD) vaccines, while effective in preventing tumours, do not prevent viral replication and mutation, which has been hypothesized as the major driving force for...

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PMID: 31184569
DOI: 10.1099/jgv.0.001288

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