Article
The Pathogenic Potential of Proteus mirabilis Is Enhanced by Other Uropathogens during Polymicrobial Urinary Tract Infection.
Infection and immunity - 1 Feb 2017
Armbruster Chelsie E, Smith Sara N, Johnson Alexandra O, DeOrnellas Valerie, Eaton Kathryn A, Yep Alejandra, Mody Lona, Wu Weisheng, Mobley Harry L T
Abstract excerpt
Urinary catheter use is prevalent in health care settings, and polymicrobial colonization by urease-positive organisms, such as Proteus mirabilis and Providencia stuartii, commonly occurs with long-term catheterization. We previously demonstrated that coinfection with P. mirabilis and P. stuartii increased overall urease activity in vitro and disease severity in a model of urinary tract infection (UTI). In this...
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