Article
Influence of genetic variations in platelet glycoproteins and eNOS in the development of arterial ischaemia of lower limbs in type 2 diabetes mellitus patients.
Foot (Edinburgh, Scotland) - 1 Dec 2016
Carvalhais Virginia, Ruivães Ema, Pina-Cabral Luis Bernardo, Mesquita Bárbara, Oliveira Flávio, Monteiro Maria Céu, Criado Maria Begoña
Abstract excerpt
Endothelial and platelet dysfunction increase the atherothrombotic risk in diabetes mellitus patients. Therefore, arterial ischaemia of lower limbs is an important complication in diabetes mellitus. In the present work, type 2 diabetic patients were classified by a podiatrist into presence or absence of arterial ischaemia of lower limbs. Several polymorphisms in platelet glycoproteins and eNOS genes were...
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