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An association between fibrinogen gene polymorphisms and diabetic peripheral neuropathy in young patients with type 1 diabetes.

Molecular biology reports - 1 May 2021

Vojtková Jarmila, Kolková Zuzana, Motyková Katarína, Kostková Martina, Suroviaková Stanislava, Grendár Marián, Bánovčin Peter

Abstract excerpt

In complex etiopathogenesis of diabetic peripheral neuropathy (DPN), hemostatic dysfunction and subclinical inflammation play a possible role. Fibrinogen is involved in both the hemostatic and inflammatory pathways, so we hypothesize that fibrinogen gene polymorphisms might be associated with DPN. A total of 127 young patients with type 1 diabetes (T1D) (average age, 18.5 ± 4.65 years; average diabetes duration,...

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PMID: 34061326
DOI: 10.1007/s11033-021-06455-1

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