Article
Melatonin and hydroxytyrosol-rich wines influence the generation of DNA oxidation catabolites linked to mutagenesis after the ingestion of three types of wine by healthy volunteers.
Food & function - 7 Dec 2016
Marhuenda Javier, Medina Sonia, Martínez-Hernández Pedro, Arina Simón, Zafrilla Pilar, Mulero Juana, Genieser Hans-Gottfried, Ferreres Federico, Gil-Izquierdo Ángel
Abstract excerpt
The Mediterranean Diet (MD) has been proved to exert benefits with respect to the maintenance of the redox balance, and wine is a representative component. Bioactive compounds such as polyphenols, melatonin and hydroxytyrosol act as radical scavengers and regulate the oxidation status of organisms. Oxidative damage to DNA yields a large range of end products. The repair of oxidized DNA entails the removal of the...
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