Article
Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.
Science translational medicine - 23 Nov 2016
Wagner Vitas E, Dey Neelendu, Guruge Janaki, Hsiao Ansel, Ahern Philip P, Semenkovich Nicholas P, Blanton Laura V, Cheng Jiye, Griffin Nicholas, Stappenbeck Thaddeus S, Ilkayeva Olga, Newgard Christopher B, Petri William, Haque Rashidul, Ahmed Tahmeed, Gordon Jeffrey I
Abstract excerpt
To model how interactions among enteropathogens and gut microbial community members contribute to undernutrition, we colonized gnotobiotic mice fed representative Bangladeshi diets with sequenced bacterial strains cultured from the fecal microbiota of two 24-month-old Bangladeshi children: one healthy and the other underweight. The undernourished donor's bacterial collection contained an enterotoxigenic...
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