Article
The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium.
Genetics - 1 Jan 2017
Zaitlen Noah, Huntsman Scott, Hu Donglei, Spear Melissa, Eng Celeste, Oh Sam S, White Marquitta J, Mak Angel, Davis Adam, Meade Kelly, Brigino-Buenaventura Emerita, LeNoir Michael A, Bibbins-Domingo Kirsten, Burchard Esteban G, Halperin Eran
Abstract excerpt
Statistical models in medical and population genetics typically assume that individuals assort randomly in a population. While this simplifies model complexity, it contradicts an increasing body of evidence of nonrandom mating in human populations. Specifically, it has been shown that assortative mating is significantly affected by genomic ancestry. In this work, we examine the effects of ancestry-assortative...
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