Article
Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America - 29 Nov 2016
Eldholm Vegard, Pettersson John H-O, Brynildsrud Ola B, Kitchen Andrew, Rasmussen Erik Michael, Lillebaek Troels, Rønning Janne O, Crudu Valeriu, Mengshoel Anne Torunn, Debech Nadia, Alfsnes Kristian, Bohlin Jon, Pepperell Caitlin S, Balloux Francois
Abstract excerpt
The "Beijing" Mycobacterium tuberculosis (Mtb) lineage 2 (L2) is spreading globally and has been associated with accelerated disease progression and increased antibiotic resistance. Here we performed a phylodynamic reconstruction of one of the L2 sublineages, the central Asian clade (CAC), which has recently spread to western Europe. We find that recent historical events have contributed to the evolution and...
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