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Article

Respiration supports intraphagosomal filamentation and escape of Candida albicans from macrophages

1 Dec 2023

Abstract excerpt

ABSTRACT For the human fungal pathogen Candida albicans , metabolic flexibility and the ability to transition between yeast and filamentous growth states are key virulence traits that enable disease in the host. These traits are particularly important during the interaction of C. albicans with macrophages, where the fungus must utilize multiple alternative carbon sources to survive after being phagocytosed, and...

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PMID: 38038475
DOI: 10.1128/mbio.02745-23

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