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Article

Genetic analysis of the CITED2 gene promoter in isolated and sporadic congenital ventricular septal defects.

Journal of cellular and molecular medicine - 1 Feb 2021

Zheng Si-Qiang, Chen Huan-Xin, Liu Xiao-Cheng, Yang Qin, He Guo-Wei

Abstract excerpt

Ventricular septal defect (VSD) is the most common congenital heart defect. Previous studies have reported genetic variations in the encoding region of CITED2 highly associated with cardiac malformation but the role of CITED2 gene promoter variations in VSD patients has not yet been explored. We investigated the variation of CITED2 gene promoter and its impacts on gene promoter activity in the DNA of paediatric...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33439552
DOI: 10.1111/jcmm.16218
PMCID: PMC7882930

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