Article
Genomic epidemiology of Lineage 4 Mycobacterium tuberculosis subpopulations in New York City and New Jersey, 1999-2009.
BMC genomics - 21 Nov 2016
Brown Tyler S, Narechania Apurva, Walker John R, Planet Paul J, Bifani Pablo J, Kolokotronis Sergios-Orestis, Kreiswirth Barry N, Mathema Barun
Abstract excerpt
BACKGROUND: Whole genome sequencing (WGS) has rapidly become an important research tool in tuberculosis epidemiology and is likely to replace many existing methods in public health microbiology in the near future. WGS-based methods may be particularly useful in areas with less diverse Mycobacterium tuberculosis populations, such as New York City, where conventional genotyping is often uninformative and field...
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