Article
Genomic diversity in Onchocerca volvulus and its Wolbachia endosymbiont.
Nature microbiology - 21 Nov 2016
Choi Young-Jun, Tyagi Rahul, McNulty Samantha N, Rosa Bruce A, Ozersky Philip, Martin John, Hallsworth-Pepin Kymberlie, Unnasch Thomas R, Norice Carmelle T, Nutman Thomas B, Weil Gary J, Fischer Peter U, Mitreva Makedonka
Abstract excerpt
Ongoing elimination efforts have altered the global distribution of Onchocerca volvulus, the agent of river blindness, and further population restructuring is expected as efforts continue. Therefore, a better understanding of population genetic processes and their effect on biogeography is needed to support elimination goals. We describe O. volvulus genome variation in 27 isolates from the early 1990s (before...
Topics
- Africa, Western
- Animals
- Ecuador
- Gene Flow
- Genetic Variation
- Genotype
- Onchocerca volvulus
- Phylogeography
- Uganda
- Wolbachia