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Article

Recent evolutionary history of American Onchocerca volvulus, based on analysis of a tandemly repeated DNA sequence family.

1 May 1994

Abstract excerpt

Polymerase chain reaction (PCR) products were characterized for a repeated sequence family (designated "O-150") of the human filarial parasite Onchocerca volvulus. In phylogenetic inferences, the O-150 sequences clustered into closely related groups, suggesting that concerted evolution maintains sequence homology in this family. Using a novel mathematical model based on a nested application of an analysis of...

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PMID: 7516998
DOI: 10.1093/oxfordjournals.molbev.a040114

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