Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic structuring and estimation of reproductive adults in Onchocerca volvulus: A genome-wide analysis across hosts and regions.

PLoS neglected tropical diseases - 1 Jul 2025

Kumar Pawan, Choi Young-Jun, Fischer Kerstin, Hedtke Shannon M, Kode Anusha, Opoku Nicholas, Gankpala Lincoln, Ukety Tony O, Mande Jöel Lonema, Anderson Timothy J C, Grant Warwick N, Fischer Peter U, Mitreva Makedonka

Abstract excerpt

Genomic analysis of parasites can deepen our understanding of their transmission, population structure, and important biological characteristics. Onchocerciasis (river blindness), caused by the parasitic nematode Onchocerca volvulus, involves adult worms residing in subcutaneous nodules that produce larval-stage microfilariae (mf), which are routinely detected in the skin for diagnosis. Whole-genome studies of mf...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Democratic Republic of the Congo
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Helminth

Share to Reproduction

Source

Open in PubMed Open full text

Identifiers

PMID: 40591654
DOI: 10.1371/journal.pntd.0013221
PMCID: PMC12212510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic structuring and estimation of reproductive adults in Onchocerca volvulus: A genome-wide analysis across hosts and regions.PMID 40591654Read ↗

Genome-based tools for onchocerciasis elimination: utility of the mitochondrial genome for delineating Onchocerca volvulus transmission zonesSemantic proximity Read ↗

Utility of the <i>Onchocerca volvulus</i> mitochondrial genome for delineation of parasite transmission zonesSemantic proximity Read ↗

Distinguishing recrudescence from reinfection in lymphatic filariasis: a genomics-based approach for monitoring worm burdenSemantic proximity Read ↗

Estimating the number of breeders from helminth larvae with genomic dataSemantic proximity Read ↗

Distinguishing recrudescence from reinfection in lymphatic filariasis.Semantic proximity Read ↗

Genomic diversity in Onchocerca volvulus and its Wolbachia endosymbiont.Semantic proximity Read ↗

Assessing Onchocerca volvulus Intensity of Infection and Genetic Diversity Using Mitochondrial Genome Sequencing of Single Microfilariae Obtained before and after Ivermectin TreatmentSemantic proximity Read ↗

Full mitochondrial and nuclear genome comparison confirms that Onchocerca sp. "Siisa" is Onchocerca ochengi.Semantic proximity Read ↗

Molecular phylogeny of the filaria genus Onchocerca with special emphasis on Afrotropical human and bovine parasitesSemantic proximity Read ↗

Reproductive biology of Onchocerca ochengi, a nodule forming filarial nematode in zebu cattle.Semantic proximity Read ↗

Molecular epidemiology of Schistosoma mansoni: a robust, high-throughput method to assess multiple microsatellite markers from individual miracidia.Semantic proximity Read ↗

Genome structure and population genomics of the canine heartworm Dirofilaria immitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.