Article
Role of miR-139 as a surrogate marker for tumor aggression in breast cancer.
Human pathology - 1 Mar 2017
Dai Hongyan, Gallagher Dan, Schmitt Sarah, Pessetto Ziyan Y, Fan Fang, Godwin Andrew K, Tawfik Ossama
Abstract excerpt
MicroRNAs are non-protein coding molecules that play a key role in oncogenesis, tumor progression, and metastasis in many types of malignancies including breast cancer. In the current study, we studied the expression of microRNA-139-5p (miR-139) in invasive ductal carcinoma (IDC) of the breast and correlated its expression with tumor grade, molecular subtype, hormonal status, human epidermal growth factor...
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