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Gut microbiome in children with enthesitis-related arthritis in a developing country and the effect of probiotic administration

10 Nov 2016

Abstract excerpt

In Asia, enthesitis-related arthritis (ERA) is the most frequent category of juvenile idiopathic arthritis. ERA has a strong association with human leucocyte antigen (HLA)-B27 and subclinical gut inflammation. In an HLA-B27 transgenic rat model, the presence of Bacteroides bacteria in the gut appears to cause spondyloarthropathy (SpA). Thus, we studied gut microbiota in children with ERA. Stool specimens from 33...

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PMID: 27861762
DOI: 10.1111/cei.12900

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