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Article

TLR4/CD14 Variants-Related Serologic and Immunologic Dys-Regulations Predict Severe Sepsis in Febrile De-Compensated Cirrhotic Patients.

PloS one - 1 Jan 2016

Fan Wen-Chien, Liu Chih-Wei, Ou Shuo-Ming, Huang Chia-Chang, Li Tzu-Hao, Lee Kuei-Chuan, Huang Shiang-Fen, Yang Ying-Ying, Hsieh Yun-Cheng, Hsieh Shie-Liang, Hou Ming-Chih, Lin Han-Chieh

Abstract excerpt

Genetic variants and dysfunctional monocyte had been reported to be associated with infection susceptibility in advanced cirrhotic patients. This study aims to explore genetic predictive markers and relevant immune dysfunction that contributed to severe sepsis in febrile acute de-compensated cirrhotic patents. Polymorphism analysis of candidate genes was undergone in 108 febrile acute de-compensated cirrhotic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27861595
DOI: 10.1371/journal.pone.0166458
PMCID: PMC5115743

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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