Article
Associations between a Genetic Risk Score for Clinical CAD and Early Stage Lesions in the Coronary Artery and the Aorta.
PloS one - 1 Jan 2016
Salfati Elias L, Herrington David M, Assimes Themistocles L
Abstract excerpt
OBJECTIVE: The correlation between the extent of fatty streaks, more advanced atherosclerotic lesions, and community rates of coronary artery disease (CAD) is substantially higher for the coronary artery compared to the aorta. We sought to determine whether a genetic basis contributes to these differences. APPROACH AND RESULTS: We conducted a cluster analysis of 6 subclinical atherosclerosis phenotypes documented...
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