Article
Rhinosinusitis in the pediatric patient with cystic fibrosis.
Current pediatric reviews - 1 Jan 2014
Fundakowski Christopher, Ojo Rosemary, Younis Ramzi
Abstract excerpt
Cystic fibrosis (CF) is a common autosomal recessive genetic disorder where a deletion mutation and subsequent downstream alteration in transmembrane regulator proteins results in increased mucus viscosity. CF manifests clinically with chronic multisystem inflammation and recurrent infections. Nearly all children with CF have chronic sinusitis, and a large majority will have concurrent sinonasal polyposis....
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