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Article

The prevalence of CFTR mutations in patients with chronic rhinosinusitis: A systematic review and meta-analysis.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery - 1 Jan 2022

Yong Michael, Hernaiz-Leonardo Juan Carlos, Alqunaee Marwan, Quon Bradley S, Javer Amin

Abstract excerpt

OBJECTIVES: Undetected cystic fibrosis transmembrane regulator (CFTR) mutations may predispose individuals to develop CRS independent of formal CF diagnosis. The objective of this study was to determine the prevalence of CFTR mutations among individuals with CRS. DESIGN: A systematic search following PRISMA guidelines was performed. A meta-analysis was performed to calculate pooled estimates for the prevalence of...

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Identifiers

PMID: 34664411
DOI: 10.1111/coa.13875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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