Article
Intratumor stromal proportion predicts aggressive phenotype of gastric signet ring cell carcinomas.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jul 2017
Lee Dakeun, Ham In-Hye, Son Sang Yong, Han Sang-Uk, Kim Young-Bae, Hur Hoon
Abstract excerpt
OBJECTIVE: The aim of this study was to evaluate the prognostic significance of the intratumor stromal proportion in gastric signet ring cell (SRC) carcinomas. BACKGROUND: Cancer stroma, as exemplified by cancer-associated fibroblasts (CAFs), plays critical roles in cancer proliferation, invasion, and metastasis. METHODS: One hundred seventy-five SRC carcinoma cases were classified according to the intratumor...
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