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Article

A Non-Human Primate Model of Severe Pneumococcal Pneumonia.

PloS one - 1 Jan 2016

Reyes Luis F, Restrepo Marcos I, Hinojosa Cecilia A, Soni Nilam J, Shenoy Anukul T, Gilley Ryan P, Gonzalez-Juarbe Norberto, Noda Julio R, Winter Vicki T, de la Garza Melissa A, Shade Robert E, Coalson Jacqueline J, Giavedoni Luis D, Anzueto Antonio, Orihuela Carlos J

Abstract excerpt

RATIONALE: Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and infectious death in adults worldwide. A non-human primate model is needed to study the molecular mechanisms that underlie the development of severe pneumonia, identify diagnostic tools, explore potential therapeutic targets, and test clinical interventions during pneumococcal pneumonia. OBJECTIVE: To develop a non-human...

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Identifiers

PMID: 27855182
DOI: 10.1371/journal.pone.0166092
PMCID: PMC5113940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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