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Article

Sil1-Mutant Mice Elucidate Chaperone Function in Neurological Disorders.

Journal of neuromuscular diseases - 27 May 2016

Buchkremer Stephan, González Coraspe José Andrés, Weis Joachim, Roos Andreas

Abstract excerpt

Chaperone dysfunction leading to the build-up of misfolded proteins could frequently be linked to clinical manifestations also affecting the nervous system and the skeletal muscle. In addition, increase in chaperone function is beneficial to antagonize protein aggregation and thus represents a promising target for therapeutic concepts for many genetic and acquired chaperonopathies. However, little is known on the...

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Source

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Identifiers

PMID: 27854219
DOI: 10.3233/JND-160152
PMCID: PMC5271578

Genes

SIL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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