Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative mutation, haplotype and G × G interaction evidence connects ABGL4, LRP8 and PCSK9 genes to cardiometabolic risk.

Scientific reports - 17 Nov 2016

Guo Tao, Yin Rui-Xing, Yao Li-Mei, Huang Feng, Pan Ling, Lin Wei-Xiong, Yang De-Zhai, Pan Shang-Ling

Abstract excerpt

This study is expected to investigate the association of ATP/GTP binding protein-like 4 (AGBL4), LDL receptor related protein 8 (LRP8) and proprotein convertase subtilisin/kexin type 9 (PCSK9) gene single nucleotide variants (SNVs) with lipid metabolism in 2,552 individuals (Jing, 1,272 and Han, 1,280). We identified 12 mutations in this motif. The genotype and allele frequencies of these variants were different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-I
Share to Apolipoproteins B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carboxypeptidases

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to LDL-Receptor Related Proteins

Share to Metabolic Syndrome

Share to Proprotein Convertase 9

Source

Open in PubMed Open full text

Identifiers

PMID: 27853278
DOI: 10.1038/srep37375
PMCID: PMC5112603

Genes

LRP8
PCSK9
AGBL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative mutation, haplotype and G × G interaction evidence connects ABGL4, LRP8 and PCSK9 genes to cardiometabolic risk.PMID 27853278Read ↗

Association between the DOCK7, PCSK9 and GALNT2 Gene Polymorphisms and Serum Lipid levels.Semantic proximity Read ↗

Genetic Regulatory Networks of Apolipoproteins and Associated Medical RisksSemantic proximity Read ↗

Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.Semantic proximity Read ↗

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.Semantic proximity Read ↗

Genetic Determinants of Atherogenic IndexesSemantic proximity Read ↗

Association of the variants and haplotypes in the DOCK7, PCSK9 and GALNT2 genes and the risk of hyperlipidaemia.Semantic proximity Read ↗

Regulome-SNP and Novel Risk Markers of CHD Susceptibility in the Yanbian AreaSemantic proximity Read ↗

Both rare and common variants in PCSK9 influence plasma low-density lipoprotein cholesterol level in American Indians.Semantic proximity Read ↗

An overview of the Guangzhou biobank cohort study-cardiovascular disease subcohort (GBCS-CVD): a platform for multidisciplinary collaboration.Semantic proximity Read ↗

Proprotein Convertase Subtilisin/Kexin Type 9 Gene Polymorphism (PCSK9) in Coronary Heart DiseasesSemantic proximity Read ↗

[Genetic determination of dyslipidemia - What tell us the results of genome-wide association studies?]Semantic proximity Read ↗

A Western-style diet interacts with genetic variants of the LDL receptor to hyper-LDL cholesterolemia in Korean adultsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.