Article
HEART UK statement on the management of homozygous familial hypercholesterolaemia in the United Kingdom.
Atherosclerosis - 1 Dec 2016
France Michael, Rees Alan, Datta Dev, Thompson Gilbert, Capps Nigel, Ferns Gordon, Ramaswami Uma, Seed Mary, Neely Dermot, Cramb Robert, Shoulders Carol, Barbir Mahmoud, Pottle Alison, Eatough Ruth, Martin Steven, Bayly Graham, Simpson Bill, Halcox Julian, Edwards Ray, Main Linda, Payne Jules, Soran Handrean
Abstract excerpt
This consensus statement addresses the current three main modalities of treatment of homozygous familial hypercholesterolaemia (HoFH): pharmacotherapy, lipoprotein (Lp) apheresis and liver transplantation. HoFH may cause very premature atheromatous arterial disease and death, despite treatment with Lp apheresis combined with statin, ezetimibe and bile acid sequestrants. Two new classes of drug, effective in...
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