Article
Current treatments for the management of homozygous familial hypercholesterolaemia: a systematic review and commentary.
European journal of preventive cardiology - 11 Nov 2024
Gu Jing, Gupta Rupal N, Cheng Henry K, Xu Yingxin, Raal Frederick J
Abstract excerpt
AIMS: Homozygous familial hypercholesterolaemia (HoFH) is a rare disorder characterized by markedly elevated circulating low-density lipoprotein cholesterol (LDL-C) from birth. This review aimed to critically evaluate treatments for HoFH with respect to their efficacy, safety, accessibility, overall context and position within the treatment pathway. METHODS AND RESULTS: A mixed-methods review was undertaken to...
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