Article
Chemical tools for dissecting bacterial physiology and virulence.
Biochemistry - 22 Sept 2009
Stanley Sarah A, Hung Deborah T
Abstract excerpt
Increasingly, chemical biology is being used in the context of bacterial virulence and the host-pathogen interaction, as small molecule inhibitors provide a number of unique advantages for the study of bacterial pathogens that complement powerful, existing classical genetic approaches. Small molecules have the potential to inhibit targets rapidly and reversibly, with a high degree of specificity. They are...
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