Article
Breast conservation following neoadjuvant therapy for breast cancer in the modern era: Are we losing the opportunity?
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Dec 2016
Criscitiello C, Curigliano G, Burstein H J, Wong S, Esposito A, Viale G, Giuliano M, Veronesi U, Santangelo M, Golshan M
Abstract excerpt
The main rationale for neoadjuvant therapy for breast cancer is to provide effective systemic treatment while surgically down-staging the cancer. This down-staging was initially to convert inoperable patients to operable and later to increase rates of breast conservation in patients initially deemed mastectomy only candidates. Unexpectedly, in recent neoadjuvant trials lower rates of breast conservation have been...
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