Article
Neoadjuvant chemotherapy and targeted therapies: a promising strategy.
Journal of the National Cancer Institute. Monographs - 1 Jan 2011
Metzger-Filho Otto, de Azambuja Evandro
Abstract excerpt
Neoadjuvant therapy in breast cancer has emerged as an important setting for the development of targeted drugs. Because tumor material is available before treatment, at the moment of surgery, and possibly during treatment, precise correlations can be made between target identification, target blockade, and tumor response. Significant improvements have already been achieved by introducing targeted agents to...
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